In this paper, the sinc collocation method is proposed for solving linearand nonlinear multi-order fractional di erential equations based on the newde nition of fractional derivative which is recently presented by Khalil, R., Al Horani, M., Yousef, A. and Sababeh, M. in A new de nition of fractionalderivative, J. Comput. Appl. Math. 264 (2014), 65{70. The propertiesof sinc functions are used to reduce the fractional di erential equation to asystem of algebraic equations. Several numerical examples are provided toillustrate the accuracy and e ectiveness of the presented method.